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We are sorry if we have a copy of the same page in our database.This is my work blog where I write about my life, crafts, and my views on the world. Here are my views on life and everything in between
Friday, January 21, 2011
Oscar
I don’t have any Oscars, so I got two lovely prizes for my birthday – one of which I could have gotten in November, but I was waiting for our new bean, so I couldn’t touch it.
Sorry for the delay, but we got ourselves a bean! I was not looking forward to it, but it has not been a bad experience. He’s from Linda, she is a lovely pet. I almost purchased her when I was in Tarzana with my mom, but I had no idea that Linda was still on the market. I also paid a little more than the asking price, but I will not regret it. I will be looking up Linda next week to get some advice on him.
I just got my first set of presents, a journal from Purdue and ribbon from Michael’s! I am so excited, I will get him put together on the computer so you can get a peek at it. I still have to work on the journals to get out some of the mementos. I also have some mementos myself, I will get pictures of those too in the near future.In vitro and in vivo activity of clofarabine against malignant and normal hematopoietic cells.
Clofarabine, a new nucleoside analogue, is active against acute nonlymphocytic leukemias, both in adults and children. Since clofarabine has shown potent activity against childhood acute lymphoblastic leukemia (ALL), we evaluated its activity against blasts from children with ALL, acute myeloid leukemia (AML), and other non-ALL malignancies, comparing its activity against ALL blasts in vitro with that against human peripheral blood mononuclear cells (PBMCs) in vitro and in vivo. Clofarabine was highly active against ALL blasts (mean IC(50) = 0.33 microM) and AML blasts (mean IC(50) = 0.06 microM), but had no activity against PBMCs from normal adults (mean IC(50) > 10 microM). In vivo, clofarabine showed potent activity in a murine model of human ALL
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