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Buy Magix Music Maker Soundpools 9 To 18: Video Software, Video Software downloads at Software4.Me. Magix Music Maker Soundpools 9 To 18 01.Tryptophan is an essential amino acid and is metabolized by various metabolic pathways. It has been known that in the central nervous system (CNS) and in peripheral tissues of mammals, serotonin, a neurotransmitter and a hormone, is produced from tryptophan.
An enzyme involved in the serotonin synthesis is tryptophan hydroxylase (TPH), and the resultant serotonin is decomposed by serotonin oxidase (5-H-tryptophan: oxygen oxidoreductase, 5-HTP-O-oxidase, EC 1.14.18.1) into 5-hydroxytryptamine (hereinafter referred to as “5-HT”). 5-HT is decomposed into 5-hydroxyindoleacetic acid by an aromatic amino acid decarboxylase, and then converted into 5-hydroxytryptamine acid (5-HT) by a serotonin-N-acetyl-transferase. Then, 5-HT is hydrolyzed into an indole ring by a monoamine oxidase, and then into melatonin by a peroxidase. The above reactions are conducted mainly in the brain. In addition, 5-HT is also synthesized in many peripheral tissues such as the intestine, the lung, the kidney, the liver, the mammary gland, and the uterus, and the amount of 5-HT in peripheral tissues is smaller than that in the CNS.
Thus, it is considered that the above various metabolic reactions are involved in a balance of 5-HT in the body. It is known that the tryptophan hydroxylase activity is regulated by various factors including the amount of 5-HT existing in the body, the structure and the activity of the enzyme itself, and its regulation mechanism has been gradually elucidated (see, for example, Juorio et al., Biochem. Biophys. Res. Commun., 2001, 282: 18-25).
In the living body, peripheral tissues generally have an abundant supply of tryptophan, and 5-HT synthesized by

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