Free Download Hindi Movies Ishaqzaade In Hdgolkes
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Video duration : 05 minutes, 02 seconds :: Released date : October, 2012 :: Width : 1280 :: Height : 720 :: Bitrate : 726 Kbps :: Format : MP4 :: Source : Vimeo :: Language : Hindi :: Subtitle : English :: View : 3017 times ::
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We examined the effects of UFT and its metabolite 5-fluorouracil (5-FU) on DNA replication in two human colonic cancer cell lines. These cells were identified as HCT-15 and HT-29. They were treated with UFT and 5-FU at low concentrations (0.01 to 10 microM) to allow the comparison of the effects of the two agents on DNA synthesis with and without liver S9 fraction and P450-induced inactivation. Cell cycle profiles were analyzed by flow cytometry. DNA synthesis in the UFT-treated cells was inhibited to some extent, but not significantly. On the other hand, 5-FU suppressed DNA synthesis to a significantly greater extent than UFT. When the cells were treated with both UFT and 5-FU, they showed a significant inhibition of DNA synthesis. These results suggest that UFT and 5-FU may have different effects on the cells and the combined effect is greater than their individual effects./*
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